The Spanish Society of Pneumology and Thoracic Surgery (SEPAR) has granted a project leaded by Dr. Vilaplana to study the lesions from TB patients undergoing therapeutical surgery in the National Center for Tuberculosis and Lung Diseases (NCTLD) in Tbilisi, Georgia. This grant will help to fund the SH-TBL project (clinicaltrials.gov identifier: NCT02715271), which PI is Dr. Vilaplana and is currently being conducted in collaboration with Dr. Sergo Vashakidze and Dr. Natalia Schubladze (NCTLD).
The correlation of the morphologic, microbiological, genetic and histopathological characteristics of TB lesions obtained in therapeutical surgery with the clinical forms and features of the patients will provide essential information
- on the role of the host in the mechanisms associated to the generation and evolution of active TB and
- about future diagnostic and/or prognostic biomarkers of TB disease. All this information could be used for patients stratification and/or to design new therapeutic strategies.
The project has started received finantial support from ISCIII-Subdirección General de Evaluación and Fondo-EU de Desarrollo Regional (FEDER) through Dr. Vilaplana’s contract CP13/00174 and the associated project; and the SEPAR’s grant will help to recruit more patients to the study.