New paper: Review on NSAIDS for TB

Lengthy, antimicrobial therapy targeting the pathogen is the mainstay of conventional tuberculosis treatment, complicated by emerging drug resistances. We have been working on Host-directed therapies, mainly in non-steroidal anti-inflammatory drugs (NSAIDs), since 2010.  In collaboration with our colleagues from the University Medical Center Groningen and the HDT-Network, we have just published in Frontiers Immunology Journal a  Systematic Review in which investigate whether NSAIDs display any effects as therapy of TB. We have included ten studies, seven preclinical studies in mice and three clinical trials. Our results point toward a beneficial effect of NSAIDs as adjunct to current TB therapy regimens, even if the determination of the best timing for their administration needs further investigation.

You can read and download the paper here.

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Do you want to work with us? we are looking for post-docs

We are looking for a bright, motivated post-doc to apply to theMarie Curie Sklodowska Programme 2016-17 European Fellowships. You can see most of our work in this blogsite, check our research lines,, our papers and the pictures! We want an open-minded individual, eager to learn, able to travel and wanting to spend some lifetime in our beautiful city. Doing research while having sun most days of the year? Yes, it is possible!

If you are interested, please check the call here and follow the instructions: 2017_42 Post doctoral Marie Curie Sklodowska Programme 2016-17 European Fellowships 

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Specialization Course in Clinical TB Management

A new edition of the  Specialization Course in Clinical TB Management will be soon launched in the Open University of Catalonia (UOC). Coordinated by Pr. Pere-Joan Cardona, and counting with Dr. Vilaplana as professor, this online course is open to worldwide professionals to be trained to face new challenges in TB management from an innovative and up-to-date perspective. The main objective of the course is to provide the theoretical and practical background necessary for proper clinical management of tuberculosis through knowledge of the histopathological basis of the disease’s evolution. Through this specialization, the student will be updated on recent discoveries surrounding the natural history of tuberculosis, including new tools for diagnosis, prevention and treatment. The course is designed to be taken in a single semester (March-July), and starts on the 15th March 2017.

Are you interested? Please CLICK HERE.


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PhD position – Do you want to work with us?

Thanks to the INPhINIT call of LaCaixa Foundation, we are happy to offer a PhD position in our lab. INPhINIT is a new doctoral fellowship programme devoted to attracting international Early-Stage Researchers to the top Spanish research centres. The Programme recruits per call 57 Early-Stage Researchers of any nationality, who enjoy a 3-year employment contract at the Research Centre of their choice among those selected and awarded by the Spanish Ministry of Economy and Competitiveness (“Severo Ochoa” centres of excellence and “Maria de Maeztu” units of excellence) and the Spanish Ministry of Health (“Carlos III centres of excellence“). In addition, researchers establish a personal career development plan including trasnational, intersectoral and interdisciplinary mobility opportunities, and attend a full range of complementary training courses and workshops. INPhINIT relies on the European Commission’s support through the Horizon 2020 Marie Skłodowska-Curie Actions – COFUND programme to recruit a larger number of researchers and achieve a broader impact, as well as to further pursue the highest standards for research training.

One of the research lines of our Unit, leaded by Dr. Vilaplana, is devoted to study  the active tuberculosis and its course, the role of inflammation in its development and evolution, and its modulation through Host-Directed Therapies (HDT). We study biomarkers in the context of the clinical and radiological manifestations of the disease, as well as the other characteristics (epidemiologic, demographic, comorbidities, microbiological and histopathology, and Health Quality of Life data). Thanks to our participation in several International consortia, we have a strong multidisciplinary network, and our collaborators are based in Europe, Tbilisi (Georgia) and Africa (SouthAfrica, Angola, Ethiopia). We now propose a vacancy to help evaluating all these aspects in our  clinical studies; and to actively  participate in the communication activities  and intervention strategies to be designed and developed in field. We do offer a position to obtain multiple skills at translational level, the mobility to gain expertise in different settings, and all the education and training tools available in our Campus.

CHECK FOR THE REQUISITES AND APPLY FOR IT! The end of the call for applications is 2 February 2017

At this position, the candidate will have the possibility to have an impact in tuberculosis management, so in tuberculosis patients. This is a Health Sciences Project, but with multidisciplinary aspects including immunology, social sciences, psychology and medicine. For all these, we look for an open minded person, willing to travel and to do internships abroad, and speaking english (compulsory). Because of our collaborators’ origin, speaking other languages will be much appreciated (preferred: Russian, Spanish and/or French). Candidates should have a background in medicine, biomedicine, psychology or in other bio/health sciences. Students with social sciences background are also invited to apply. Medical students will be prioritized. No previous lab experience is needed, but past experience will be taken into account. Candidates should be willing to obtain a multidisciplinary education during the PhD, and to participate in dissemination activities as talks and oral communications. Team work is essential to this position, and we do expect the candidate to respect both hierarchy and the other members of the team. Ability to work successfully in a dynamic and fast paced environment as team member and independently is essential. References will be welcomed.

To learn more about the Programme, please CLICK HERE. 


  1. Go to the webpage: 
  2. Fill in the FINDER blanks as follows: 
    • Area of knowledge:  select the option “Life Science Panel”
    • Disciplines:  select the option “Medicine, Public Health, Sport Sciences, Nutrition, Clinical Psychology, HealthCare Management”
    • Province: select the option “Barcelona”
    • Research Center: select the option “Germans Trias i Pujol Research Institute- IGTP”
    • Search by Project Title/Job Position Title: please write “Tuberculosis”
  3. Click the SEARCH button
  4. Our position will appear below, under the sentence “Experimental Tuberculosis PhD position at HUGTP (Dr.Cristina Vilaplana)”. 
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We wish you all happy season’s holidays – and a healthy, fruitful 2017!

2016 is about to come to its end, and before going on season’s holidays, we would like to share with all of you our achievements. This year, we have worked a lot, but also achieved a lot!

  • We had 2 new proposals granted;
  • We got several contracts with other research institutions or private companies, and we got some donations;
  • We started 3 clinical studies, 2 of them clinical trials;
  • We generated 1 thesis and 7 papers, and we edited one Frontiers topic;
  • We hosted 5 new undergraduate/degree/master students;
  •  We welcomed 3 new PhD students, which will be doing their thesis work with us;
  • We got funding for contracting 4 persons;
  • We organised 2 international conferences

and moreover, we did all these things while working with friends, and having fun!

For all this, we are so grateful to all your help and support, and we would like to share our happiness and our best wishes with all of you, all of the scientific community working on TB, and all the TB patients.


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Fundraising event for TB patients

Promoted by Dr. Vilaplana, the UTE has been fundraising money to buy personal care products for TB inpatients staying at the Serveis Clinics Unit (SSCC), in Barcelona. This clinic is specialized in managing TB patients at risk of poverty or social exclusion. The SSCC and the UTE are already collaborating, and we do expect to be part of shared research projects very soon.

We are happy to announce that in one week we raised 229,95€, which were used to buy:

  • 9 pairs of shower slippers
  • 27 toothbrushes
  • 6 pairs of winter home slippers
  • 6 pyjamas
  • 24 knickers
  • 6 underpants

Moreover, the pharmacy  Farmàcia Coll Colomer (St. Elies, 28, Barcelona) donated spectacles for presbyopia, for current or future patients who might need them.

We would like to thank all those who generously contributed to our cause. A small gesture can achieve so much!

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The FUITB has closed its art competition. Help them to decide the winners!

Visit their website to watch the illustrations and vote!

We have the images. Please help us to decide the winners!

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